Adult orthostatic proteinuria
نویسندگان
چکیده
Orthostatic proteinuria is characterized by elevated levels of urinary protein excretion while in the upright or lordotic position and normal excretion when in the supine or recumbent position, such as that during bed rest. This type of proteinuria is the most frequent cause of isolated proteinuria in children and adolescents. In adolescents, the prevalence of orthostatic proteinuria is reported to be between 2 and 5% [1]. However, it is an uncommon disorder in individuals over 30 years of age [2]. As it is a benign condition requiring no further evaluation or specific therapy, the differential diagnosis of orthostatic proteinuria is crucial in clinical practice to avoid unnecessary interventions such as a kidney biopsy.
منابع مشابه
Pediatric Nephrology Fellowship Program at Yale University School of Medicine
Orthostatic proteinuria accounts for 60% of all children and 75% of adolescents with proteinuria. Despite its frequent occurrence, the underlying pathophysiologic mechanisms remain unclear. The following three possibilities have been reviewed: ( 1) a normal variant; (2) a glomerular abnormality; (3) a I Received June 9, 1992. Accepted November 30, 1992. 2 Correspondenceto Dr. P. Devarajan, 333 ...
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